GHK-Cu (Glycyl-L-Histidyl-L-Lysine-Copper) is a naturally occurring copper-binding peptide found in human plasma, saliva, and urine that declines with age.  It functions as a powerful signaling molecule influencing multiple cellular pathways, offering broad regenerative and protective benefits. 
Skin Health & Anti-Aging
Stimulates collagen and elastin production, improving skin firmness, elasticity, and reducing wrinkles. 
Enhances skin density, hydration, and texture, with clinical studies showing up to 30% improvement in elasticity and 25% reduction in wrinkle depth after 12 weeks of use. 
Reduces fine lines, hyperpigmentation, and photodamage while promoting keratinocyte proliferation. 
Accelerates wound healing and tissue repair, with research indicating 40–50% faster wound closure compared to controls. 
Hair Growth & Scalp Health
Promotes hair follicle stimulation and increases hair density and thickness. 
Extends the anagen (growth) phase of the hair cycle and improves scalp circulation. 
Reduces inflammation in the scalp environment, supporting healthier follicle function—particularly beneficial for androgenetic alopecia. 
Tissue Repair & Regeneration
Accelerates healing of skin, hair follicles, gastrointestinal tract, bone, and connective tissues. 
Enhances angiogenesis (new blood vessel formation), improving nutrient delivery to damaged areas. 
Restores replicative vitality to fibroblasts, even after radiation exposure.
Systemic & Cellular Benefits
Modulates over 200 genes involved in tissue repair, inflammation, oxidative stress, and aging. 
Acts as a potent antioxidant, reducing reactive oxygen species (ROS) by up to 40%.
Exhibits anti-inflammatory effects by suppressing pro-inflammatory cytokines (e.g., TNF-α, IL-1β) and NF-κB pathway activity. 
Supports neuroprotection and cognitive health, with preclinical evidence suggesting benefits in neurodegeneration and brain function. 
Delivery & Safety
Available in topical serums (0.5–2%), subcutaneous injections, and IV infusions. 
Generally safe with minimal adverse effects; rare side effects include mild irritation or allergic reactions (<2%). 
Contraindicated in Wilson’s disease, hemochromatosis, or copper metabolism disorders.
Injectable forms should only be administered under professional supervision. 
While preclinical and in vitro data are robust, human clinical trials are still emerging.  For optimal results, GHK-Cu is best used as part of a holistic wellness protocol including nutrition, sleep, and lifestyle habits.