Gonadorelin peptide stimulates the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary gland, which in turn increases sex hormone production by the gonads, including testosterone in men and estrogen and progesterone in women.
 This makes it beneficial for improving fertility in both men and women by supporting sperm production (spermatogenesis) and promoting ovulation.
 In men, gonadorelin enhances testosterone production by activating Leydig cells in the testes, which can help restore natural hormone levels after suppression from anabolic steroid use.
 It is also used to treat conditions such as hypothalamic amenorrhea, delayed puberty, and infertility.
Gonadorelin is considered fertility-friendly because it supports both LH and FSH, unlike testosterone replacement therapy (TRT), which often suppresses fertility.
 It is particularly useful in post-cycle therapy (PCT) for bodybuilders, as it helps reactivate the hypothalamic-pituitary-gonadal (HPG) axis, restoring natural testosterone production and preserving muscle mass and fertility.
 Its mechanism of action—mimicking natural gonadotropin-releasing hormone (GnRH)—allows for a more physiological restoration of hormonal balance compared to exogenous hormone replacement.
Additional benefits include improved libido, enhanced mood due to balanced reproductive hormones, and support for menstrual regularity in women with hormonal dysfunction.
 It may also be used in diagnostic testing to assess pituitary gland function.
 However, its use requires careful pulsatile dosing to avoid pituitary desensitization, and it is not approved for general anti-aging or performance enhancement purposes.