MK-677, also known as Ibutamoren, is a growth hormone secretagogue that stimulates the natural release of growth hormone (GH) and insulin-like growth factor 1 (IGF-1) by mimicking the action of ghrelin, the hunger hormone.
 This leads to a range of potential benefits, including increased lean muscle mass and strength, enhanced muscle protein synthesis, and improved recovery from workouts or injuries.
 It supports tissue repair and regeneration, which can be particularly beneficial for athletes and individuals recovering from physical stress or surgery.
Improved sleep quality is another notable effect, especially deeper REM sleep, which is crucial for muscle repair, memory consolidation, and hormonal balance.
 Many users report needing an afternoon nap after 7–14 days of use, indicating a shift in sleep architecture.
 MK-677 also contributes to better bone density and joint health by promoting collagen synthesis and reducing joint inflammation, potentially lowering the risk of osteoporosis.
Additionally, MK-677 may support anti-aging effects such as improved skin and hair health, reduced signs of aging, and enhanced mood through elevated serotonin and dopamine levels.
 It can aid in fat loss indirectly by increasing resting energy expenditure and promoting a higher lean body mass, although it does not directly target visceral fat.
 The compound is also associated with increased appetite, which can be advantageous for those aiming to gain weight or muscle mass, though it may require careful dietary management to avoid unwanted fat gain.