N-Acetyl Selank Amidate is a modified version of the original Selank peptide, designed to enhance stability, bioavailability, and duration of action.  It is primarily studied for its effects on mental health and cognitive function. 
Cognitive & Mental Health Benefits
Anxiolytic (anti-anxiety): Reduces anxiety without sedation, acting as a GABA-mimetic to calm the nervous system. 
Nootropic effects: Enhances focus, mental clarity, learning speed, and working memory. 
Mood stabilization: Modulates serotonin and dopamine levels, supporting emotional balance and reducing symptoms of depression and anhedonia. 
Neuroprotection & neuroplasticity: Increases expression of brain-derived neurotrophic factor (BDNF), promoting synaptic plasticity and long-term brain health. 
Physiological & Immune Benefits
Immune modulation: Regulates cytokine production, supporting immune system homeostasis and reducing hyper-reactivity. 
Stress resilience: Helps maintain optimal cortisol levels, improving stress tolerance and mental endurance. 
Anti-asthenic: Counters mental fatigue and boosts mental energy.
Key Advantages Over Standard Selank
Enhanced blood-brain barrier penetration
Greater resistance to enzymatic degradation
Longer half-life and sustained effects
Improved potency and dosing efficiency (250–500 mcg per dose, 1–2x daily) 
Delivery & Research Use
Preferred delivery: Intranasal spray (rapid absorption)
Also used via subcutaneous injection
Not approved for human use – strictly for laboratory research under controlled conditions