Selank is a synthetic 7-amino-acid peptide developed in Russia, derived from tuftsin, a naturally occurring immune modulator. It is primarily studied for its anxiolytic (anti-anxiety) and nootropic (cognitive-enhancing) effects.
It works by:
Modulating serotonin, dopamine, and GABA systems to regulate mood and reduce anxiety
Increasing brain-derived neurotrophic factor (BDNF), supporting neuroplasticity and cognitive function
Reducing interleukin-6 (IL-6), contributing to anti-inflammatory effects
Commonly used off-label, Selank is not FDA-approved but is available through compounding pharmacies. It is typically administered as a nasal spray, with effects noticeable within days to a week.
Benefits include:
Anxiety and stress reduction without sedation
Improved memory, focus, and learning
Mood stabilization
Immune modulation
Side effects are rare and mild, including nasal irritation, headaches, or dizziness. It is considered non-addictive and safe for short-term use.