SLU-PP-332 and BAM15 offer complementary benefits for metabolic health, primarily through distinct yet synergistic mechanisms. BAM15 acts as a mitochondrial uncoupler, increasing energy expenditure and promoting fat oxidation by reducing the efficiency of ATP production, which forces the body to burn more calories as heat, thereby supporting weight loss and reducing visceral and liver fat without suppressing appetite.
 This process enhances metabolic rate and may improve insulin sensitivity while preserving lean muscle mass.
 SLU-PP-332, on the other hand, functions as an exercise-mimetic compound that activates estrogen-related receptors (ERRs), upregulating genes involved in oxidative metabolism, mitochondrial biogenesis, and fatty acid oxidation, thereby improving metabolic flexibility and glucose handling.
 Together, the combination enhances cellular energy production by increasing both energy demand (via BAM15) and oxidative capacity (via SLU-PP-332), leading to greater total energy expenditure, improved insulin sensitivity, and more effective fat loss.
 Clinical and preclinical studies suggest this synergy may also support liver health, reduce inflammation, and offer potential anti-aging benefits by restoring youthful metabolic function.