TB500 Fragment (Thymosin Beta-4 Fragment 17-23) is a synthetic peptide derived from the naturally occurring protein thymosin beta-4 (Tβ4), designed to replicate its key regenerative properties.  It is primarily used for its ability to accelerate tissue repair, reduce inflammation, and promote healing across various tissues. 
Key Health Benefits:
Enhanced Tissue Regeneration: Promotes cell migration and angiogenesis (formation of new blood vessels), which supports faster recovery in muscles, tendons, ligaments, and skin. 
Improved Wound Healing: Shown to accelerate closure of cutaneous wounds, improve granulation tissue formation, and reduce scarring in preclinical studies. 
Joint and Connective Tissue Support: Effective in tendon and ligament repair, including conditions like tennis elbow or ACL injuries, by reducing adhesions and improving structural integrity. 
Muscle Recovery: Aids in skeletal muscle regeneration after injury, reduces fibrosis, and enhances functional recovery. 
Anti-Inflammatory Effects: Reduces levels of pro-inflammatory cytokines (e.g., TNF-α, IL-1β, IL-6) and promotes a shift toward anti-inflammatory immune responses.
Cardioprotection: Preclinical evidence suggests it can improve heart function post-infarction by reducing infarct size and enhancing cardiac microvascular density.
Potential for Chronic Conditions: May support healing in diabetic ulcers, pressure sores, and post-surgical recovery due to improved blood flow and tissue remodeling. 
Additional Considerations:
Mechanism of Action: Binds to G-actin, preventing actin polymerization and enabling enhanced cellular motility, which is critical for healing. 
Administration: Typically administered via subcutaneous injection; has high systemic bioavailability and stability. 
Synergy with Other Peptides: Often used in combination with BPC-157 (known as the "Wolverine Stack") for enhanced healing effects. 
Safety & Regulatory Status: Not approved by the FDA for human use. Limited long-term human data exists. Banned in competitive sports due to performance-enhancing potential.  Use should be under medical supervision.
While promising, most evidence is from animal studies and anecdotal reports—large-scale, controlled human trials are still lacking.  FOR RESEARCH PURPOSES ONLY.